BioCeuticals Acetyl L-Carnitine (90 capsules)

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BioCeuticals Acetyl L-Carnitine (90 capsules)

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Acetyl-L-carnitine (ALC, acetyllevocarnitine) is the naturally occurring acetyl ester of L-carnitine and is the delivery form for both L-carnitine and acetyl groups.

Carnitine is an amino acid required for normal healthy lipid and carbohydrate metabolism. It is concentrated in cardiac and skeletal cells where it helps deliver fatty acids into mitochondria for cellular energy production. High concentrations are also found in the male reproductive tract and the brain.

When acetylated in the form of ALC, it readily crosses the blood-brain barrier to support neuronal energetics and repair mechanisms while modifying acetylcholine production in the central nervous system (CNS).

 

  • Assists the transport of long-chain fatty acids (LCFA) into mitochondria, where they are oxidised for the synthesis of cellular energy.
  • Supports normal healthy lipid and carbohydrate metabolism.
  • Provides nutritional support and antioxidant protection for healthy cell membrane integrity.
  • Balances and supports normal male physiology and function.
  • Plays a role in normal healthy sperm motility.
  • Supports healthy brain function.
  • Supports healthy ageing.
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  • The ingredient in this product has not been shown to be contraindicated during pregnancy or lactation.
  • Supplementation with ALC has not been shown to produce significant side effects, even with long-term (one year) administration.[1] Infrequently, mild side effects have been reported and include gastrointestinal upset, nausea, vomiting, agitation, and fishy odour on the breath, sweat and urine.[2]
  • L-carnitine has been reported to increase the risk of seizures in those with a pre-existing condition. Theoretically, this may occur with ALC.[2,3]
  • In patients with hypothyroidism, L-carnitine seems to inhibit the activity of thyroid hormone in the target tissues. Theoretically, this may occur with ALC.[2]
  • Use with caution in patients with chronic liver disease as this condition may impair the metabolism or increase the biosynthesis of L-carnitine.[3]
  • Use with caution in patients taking warfarin and other anticoagulant drugs. L-carnitine (1g/day) has been reported in one case to increase the anticoagulant effects of acenocoumarol.[2,3]

[1] Acetyl-L-carnitine. Monograph. Altern Med Rev 2010;15(1):76-83.
[2] Acetyl-L-carnitine. Natural Medicines Comprehensive Database 2013. Viewed 11 Dec 2013, www.naturaldatabase.com
[3] Braun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 3rd ed. Sydney: Churchill Livingstone Elsevier, 2010.
[4] Hendler SS, Rorvik DM. Physicians’ desk reference for nutritional supplements, 2nd ed. Montvale: Thomson Reuters, 2008.
[5] Murray MT, Pizzorno JE Jr. Carnitine. In: Pizzorno JE Jr, Murray MT (Eds), Textbook of natural medicine, 3rd ed. (pp.809-21). St Louis: Churchill Livingstone Elsevier, 2006.
[6] L-carnitine. Micronutrient information center. Linus Pauling Institute 2007. Viewed 6 Dec 2008, http://lpi.oregonstate.edu/infocenter/othernuts/carnitine