BioCeuticals SB Floractiv® (30 capsules)

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BioCeuticals SB Floractiv® (30 capsules) - supplement facts.JPG
Bioceuticals-SBFloractiv-30capsules.jpg
BioCeuticals SB Floractiv® (30 capsules) - supplement facts.JPG

BioCeuticals SB Floractiv® (30 capsules)

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  • Heat stable (does not require refrigeration); ideal for travelling.

  • Excipient, lactose and dairy free formula.

  • Vegan friendly.

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Clinical applications of SB

  • Assists in the management of mild digestive disturbances including bloating, flatulence and digestive discomfort.[3]
  • May be used to support the relief of symptoms of antibiotic-associated or traveller's diarrhoea.[4]
  • Helps maintain healthy gastrointestinal immunity.[5,6]
  • May help decrease gastrointestinal permeability and increase the absorption of nutrients.[7]
  • Research indicates that SB may competitively inhibit the binding of Candida albicans to the gastrointestinal mucosa.[6,8]
  • May reduce inflammatory mediators in the digestive system.[9]
  • Increases the activity of the disaccharidase brush border enzymes sucrase, lactase and maltase.[10]
  • May help relieve the symptoms associated with medically diagnosed IBS.[3,11]
  • The active ingredient contained in this product has not been shown to be contraindicated during pregnancy or lactation.
  • S. boulardii has been clinically trialled in infants and children without any serious side effects reported.[1]
  • Although S. boulardii is a non-pathogenic organism, there is some concern that immunocompromised or critically ill patients taking S. boulardii may have an increased risk for fungaemia.[2]
  • Patients with long-term dysbiosis may need to start at a lower dose.
  • Patients with true (IgE-mediated) yeast allergy may be allergic to products containing S. boulardii.[2]
  • Since S. boulardii is a yeast, anti-fungal medications/herbal supplements may decrease its effectiveness.[2] Take 2 hours before or 4-6 hours after anti-fungals.

[1] Guillot CC, Bacallao EG, Dominguez MS, et al. Effects of Saccharomyces boulardii in children with chronic diarrhea, especially cases due to giardiasis. Rev Mex Pueric Pediatr 1995;2(12):1-11
[2] Saccharomyces boulardii. Natural Medicines Comprehensive Database 2014. Viewed 28 May 2014, www.naturaldatabase.com
[3] Maupas JL, Champemont P, Delforge M. Treatment of irritable bowel syndrome: double blind trial of Saccharomyces boulardii. Med Chir Dig 1983;12(1):77-79. 
[4] Kollaritsch H, Holst H, Grobara P, Wiedermann G. [Prevention of traveler’s diarrhoea with Saccharomyces boulardii. Results of a placebo controlled double-blind study]. Fortschr Med 1993;111(9):152-156. 
[5] Vandenplas Y. Bacteria and yeasts in the treatment of acute and chronic infectious diarrhea. Part II: Yeasts. Clin Microbiol Infect 1999;5(7):389-395. 
[6] Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA 1996;275(11):870-876.
[7]Garcia Vilela E, De Lourdes De Abreu Ferrari M, Oswaldo Da Gama Torres H, et al. Influence of Saccharomyces boulardii on the intestinal permeability of patients with Crohn's disease in remission. Scand J Gastroenterol 2008;43(7):842-848.
[8]Krasowska A1, Murzyn A, Dyjankiewicz A, et al. The antagonistic effect of Saccharomyces boulardii on Candida albicans filamentation, adhesion and biofilm formation. FEMS Yeast Res 2009;9(8):1312-1321.
[9]Chen X, Yang G, Song JH, et al. Probiotic yeast inhibits VEGFR signaling and angiogenesis in intestinal inflammation. PLoS One 2013;8(5):e64227. doi: 10.1371/journal.pone.0064227
[10]Jahn HU1, Ullrich R, Schneider T, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
[11]Choi CH, Jo SY, Park HJ, et al. A randomized, double-blind, placebo-controlled multicenter trial of saccharomyces boulardii in irritable bowel syndrome: effect on quality of life. J Clin Gastroenterol 2011;45(8):679-683.