BioCeuticals UltraBiotic Factors for Juniors (chewable tablets)

BioCeuticals UltraBiotic Factors for Juniors (60 chewable tablets) - supplement facts.JPG
BioCeuticals UltraBiotic Factors for Juniors (60 chewable tablets) - supplement facts.JPG

BioCeuticals UltraBiotic Factors for Juniors (chewable tablets)


UltraBiotic Factors for Juniors contains a potent blend of pre- and probiotics to help maintain healthy gastrointestinal and immune function in children. 15 billion CFU per chewable tablet - no need for refrigeration.

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The composition of children’s intestinal microflora has a huge impact on their health and wellbeing. Low bacterial diversity and numbers has been linked to a higher risk of atopy.[1-3]

The effects of probiotics on immune and digestive health are diverse and include: enhancing gut barrier function; inhibiting pathogen binding and growth; producing antimicrobial compounds; modulating gut inflammatory responses; reducing visceral hypersensitivity associated with inflammation and psychological stress; and modifying the cellular and humoral immune response (via lymphocyte activation, stimulation of phagocytosis, enhanced IgA and sIgA antibody production and INF cytokine production).[4,5]

Clinical trials investigating the use of probiotic supplements in children have revealed that they may help reduce a number of conditions, including digestive disturbances, symptoms of respiratory infections and colds, and atopic dermatitis, while also reducing antibiotic use and days missed from school.[6-12]

Prebiotics, which include oligofructosaccharides, are nondigestible foods that show resistance to gastric acidity and are fermented by the intestinal microflora. This fermentation process results in an increase in beneficial bacteria including lactobacilli and bifidobacteria.[13,14]

Supplementation with prebiotics may assist in decreasing the rate of upper respiratory tract infections in children [13,15] and support gastrointestinal health,[14] as well as providing a long term reduction in the incidence of atopic dermatitis.[16]

[1] Candela M, Rampelli S, Turroni S, et al. Unbalance of intestinal microbiota in atopic children. BMC Microbiol 2012;12:95.
[2] Wang M, Karlsson C, Olsson C, et al. Reduced diversity in the early faecal microbiota of infants with atopic eczema. J Allergy Clin Immunol 2008;121(1):129-134.
[3] Abrahamsson TR, Jakobsson HE, Andersson AF, et al. Low diversity of the gut microbiota in infants with atopic eczema. J Allergy Clin Immunol 2012;129(2):434-440.
[4] Sandhu BK, Paul SP. Irritable bowel syndrome in children: pathogenesis, diagnosis and evidence-based treatment. World J Gastroenterol 2014;20(20):6013-6023.
[5] Sarowska J, Choroszy-Kro´l I, Regulska-Ilow B, et al. The therapeutic effect of probiotic bacteria on gastrointestinal diseases. Adv Clin Exp Med 2013;22(5):759-766
[6] Yang G, Liu ZQ, Yang PC. Treatment of allergic rhinitis with probiotics: an alternative approach. N Am J Med Sci 2013;5(8):465-468.
[7] Guarino A, Canani RB, Spagnuolo MI, et al. Oral bacterial therapy reduces the duration of symptoms and of viral excretion in children with mild diarrhoea. J Pediatr Gastro Nutr 1997;25(5):516-519.
[8] Vanderhoof JA, Whitney DB, Antonson DL, et al. Lactobacillus GG in the prevention of antibiotic associated diarrhoea. J Pediatr 1999;135(5):564-568.
[9] da Costa Baptista IP, Accioly E, de Carvalho Padilha P. Effect of the use of probiotics in the treatment of children with atopic dermatitis; a literature review. Nutr Hosp 2013;28(1):16-26.
[10] Leyer GJ, Li S, Mubasher ME, et al. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 2009;124(2):e172-179.
[11] Bekkali NL, Bongers ME, Van den Berg MM, et al. The role of a probiotics mixture in the treatment of childhood constipation: a pilot study. Nutr J 2007;6:17.
[12] Guandalini S. Probiotics for children with diarrhoea: an update. J Clin Gastroenterol 2008;42 Suppl 2:S53-57.
[13] Lohner S, Ku¨llenberg D, Antes G, et al. Prebiotics in healthy infants and children for prevention of acute infectious diseases: a systematic review and meta-analysis. Nutr Rev 2014 Jun 5. [Epub ahead of print]
[14] Braun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 3rd ed. Sydney: Churchill Livingstone Elsevier, 2010.
[15] Chatchatee P, Lee WS, Carrilho E, et al. Effects of growing-up milk supplemented with prebiotics and LCPUFAs on infections in young children. J Pediatr Gastroenterol Nutr 2014;58(4):428-437.
[16] Foolad N, Armstrong AW. Prebiotics and probiotics: the prevention and reduction in severity of atopic dermatitis in children. Benef Microbes 2014;5(2):151-160.