BioCeuticals UltraBiotic Pregnancy Care (60 capsules)

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BioCeuticals UltraBiotic Pregnancy Care (60 capsules) - supplement facts.JPG

BioCeuticals UltraBiotic Pregnancy Care (60 capsules)

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Ultrabiotic Pregnancy Care is a specifically selected blend of evidence-based probiotics that supports the health of women during and after pregnancy.

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Fascinating research has uncovered new information about how beneficial microbes promote pregnancy, infant and postnatal health: they provide nutritional support for a normal healthy immune system and genitourinary tract, and help to relieve symptoms of GIT disturbances, while modulating infant growth patterns, microbiota development and reduce the incidence of atopic dermatitis and eczema.[1-10] UltraBiotic Pregnancy Care, a multispecies probiotic blend, formulated in line with this ground-breaking research. The specific species in UltraBiotic Pregnancy Care were selected based on demonstrated results in the support of common pregnancy, infant and lactation-related ailments.

Probiotic transport during pregnancy and lactation
Contrary to our past understanding, consumed probiotics are not entirely contained within the GIT. An ongoing process of systemic translocation occurs, where intestinally derived components (including probiotics and their DNA signatures) are carried by monocytes to other areas of the body.[1,2] Transport from the GIT to the lactating breast is known as the “entero-mammary pathway”. It is via this entero-mammary pathway that probiotic therapy positively influences the commensal community and probiotic DNA signatures in breast milk. On ingestion, it contributes greatly to the establishment of infant commensal communities, an important component of the infant immune defence system.

Translocation is not limited between the GIT and lactation glands. Further findings that defy our past beliefs are the discovery of probiotic species within amniotic fluid, the placenta and meconium (first stool) of neonates.[3] This is an incredible revelation, as past literature describes the infant GIT as sterile prior to delivery.

These findings have huge implications for the use of probiotics throughout pregnancy. Most recently, research suggests that these transported probiotics begin the process of foetal microbiota maturation much earlier than previously thought. 

Atopic eczema

Atopic eczema (AE) or dermatitis is an inflammatory, allergic skin condition causing itchy, inflamed, scaly skin. It can lead to significant distress from discomfort, compromised sleep patterns and interference with other aspects of life.
Based on our new understanding, it is no surprise that probiotics consumed during pregnancy and lactation (for up to six months) decrease the incidence of atopic dermatitis and eczema in the first (2-7) years of children’s lives.[4] The key species trialled here include L. rhamnosus and B. lactis.

Stool samples from infants and children with AE have significantly less lactobacilli and bifidobacteria than samples from healthy individuals. Improving colonisation of these microbes hence reduces the risk of AE development via various mechanisms. Firstly, lactic acid producing bacteria improve intestinal integrity, reducing the increased leakage of allergens from the intestine. As discussed, probiotics also modulate immune responses to allergens. They do this by influencing phagocytosis and release of sIgA and pro-inflammatory cytokines.[5,6]

Immune support
During pregnancy, there is an increased risk of certain conditions such as vaginal/urinary tract irritations and digestive disturbances.[7] Each of these conditions is associated with local dysbiosis and compromised mucosal immunity. Probiotic therapy with lactobacilli can improve urogenital health via immune modulation, pathogen displacement and creation of an environment less conducive to proliferation of pathogens.[7-9]

Digestive health
Probiotics have demonstrated effectiveness in digestive health that adds to the indications for use during pregnancy. Enhanced nutrient uptake, digestion and bowel health[10] are welcomed benefits for any expecting or lactating woman.

Recommended Dosage:

Adults: Take 1-2 capsules daily or as directed by your healthcare practitioner. 

  • Mild, temporary gastrointestinal disturbances, such as increased flatulence, may occur with amounts exceeding one billion live organisms. If this occurs reduce the dose, then gradually increase it over time. 
  • It is recommended to take probiotics at least four hours away from antibiotics to limit a potential reduction in probiotic effectiveness.

[1] Fernández L, Langa S, Martín V, et al. The human milk microbiota: origin and potential roles in health and disease. Pharmacol Res 2012. pii: S1043-6618(12)00165-X. doi: 10.1016/j.phrs.2012.09.001. [Epub ahead of print]
[2] Perez PF, Doré J, Leclerc M, et al. Bacterial imprinting of the neonatal immune system: lessons from maternal cells? Pediatrics 2007;119(3):e724-32.
[3] Rautava S, Collado MC, Salminen S, et al. Probiotics modulate host-microbe interaction in the placenta and fetal gut: a randomized, double-blind, placebo-controlled trial. Neonatology 2012;102(3):178-84.
[4] Doege K, Grajecki D, Zyriax BC, et al. Impact of maternal supplementation with probiotics during pregnancy on atopic eczema in childhood--a meta-analysis. Br J Nutr 2012;107(1):1-6.
[5] Michaelsen KF. Probiotics, breastfeeding and atopic eczema. Acta Derm Venereol Suppl (Stockh) 2005;(215):21-4.
[6] Betsi GI, Papadavid E, Falagas ME. Probiotics for the treatment or prevention of atopic dermatitis: a review of the evidence from randomized controlled trials. Am J Clin Dermatol 2008;9(2):93-103.
[7] Li J, McCormick J, Bocking A, et al. Importance of vaginal microbes in reproductive health. Reprod Sci 2012;19(3):235-42.
[8] Reid G, Dols J, Miller W. Targeting the vaginal microbiota with probiotics as a means to counteract infections. Curr Opin Clin Nutr Metab Care 2009;12(6):583-7.
[9] Reid G. Probiotic and prebiotic applications for vaginal health.Review. J AOAC Int 2012;95(1):31-4.
[10] de Milliano I, Tabbers MM, van der Post JA, et al. Is a multispecies probiotic mixture effective in constipation during pregnancy? ‘A pilot study’. Nutr J 2012;11:80. doi: 10.1186/1475-2891-11-80.